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Jakub Piątkowski, MSc

Jakub was born in Działdowo, in 1997. He received his BSc and MSc degrees at the University of Warsaw, Inter-Faculty Individual Studies in Mathematics and Natural Sciences (MISMaP), Faculty of Chemistry (both with honours). In 2021 he defended his MSc thesis titled “Synthesis and Assessment of Activated Olefin Metathesis Ruthenium Catalyst Bearing a Sildenafil-Type Sulphonamide Electron Withdrawing Group” under the supervision of prof. Karol Grela. Then, he moved to France and joined Gregory Nocton’s group at Ecole Polytechnique, where he worked on organolanthanide complexes with aromatic ligands. After a short experience in Nocton’s group, he moved to the industrial sector and held a position as medicinal chemist at Celon Pharma, where he conducted research in the development of new innovative pharmaceutical products. He joined our research group in 2024. His scientific interests cover organometallic and coordination chemistry, organic synthesis, design of novel molecules for given applications and catalysis. His current PhD project, under the supervision of dr Grzegorz Szczepaniak, is focused on the development of well-controlled polymerization systems that operate under red/NIR light.

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Publications

An isocyanide ligand for the rapid quenching and efficient removal of copper residues after Cu/TEMPO-catalyzed aerobic alcohol oxidation and atom transfer radical polymerization
G. Szczepaniak*, J. Piątkowski, W. Nogaś, F. Lorandi, S.S. Yerneni, M. Fantin, A. Ruszczyńska, A.E. Enciso, E. Bulska, K. Grela*, K. Matyjaszewski*
Chem. Sci., 2020,11, 4251-4262, DOI: 10.1039/D0SC00623H

Semiheterogeneous purification protocol for the removal of ruthenium impurities from olefin metathesis reaction products using an isocyanide scavenger
G. Szczepaniak*, W. Nogaś, J. Piątkowski, A. Ruszczyńska, E. Bulska, K. Grela*
Org. Process Res. Dev., 2019, 23, 5, 836–844, DOI: 10.1021/acs.oprd.8b00392

Olefin Metathesis in Continuous Flow Reactor Employing Polar Ruthenium Catalyst and Soluble Metal Scavenger for Instant Purification of Products of Pharmaceutical Interest
R.W. Toh, M. Patrzałek, T. Nienałtowski, J. Piątkowski, A. Kajetanowicz*, J. Wu*, K. Grela*
ACS Sustainable Chem. Eng., 2021, 9, 48, 16450–16458, DOI: 10.1021/acssuschemeng.1c06522

Back to the future of organolanthanide chemistry
N. Mahieu, J. Piątkowski, T. Simler*, G. Nocton*
Chem. Sci., 2023, 14, 443-457, DOI: 10.1039/D2SC05976B

Synthesis and Catalytic Properties of a Very Latent Selenium-Chelated Ruthenium Benzylidene Olefin Metathesis Catalyst
L. Monsigny*, J.C. Sánchez, J. Piątkowski, A. Kajetanowicz, K. Grela*
Organometallics, 2021, 40, 21, 3608–3616, DOI: 10.1021/acs.organomet.1c00484

Activated Hoveyda-Grubbs Olefin Metathesis Catalysts Derived from a Large Scale Produced Pharmaceutical Intermediate – Sildenafil Aldehyde
L. Monsigny, J. Piątkowski, D. Trzybiński, K. Woźniak, T. Nienałtowski, A. Kajetanowicz*, K. Grela*
Adv. Synth. Catal., 2021, 363, 4590, DOI: 10.1002/adsc.202100669

Anion metathesis in facile preparation of olefin metathesis catalysts bearing a quaternary ammonium chloride tag
M. Patrzałek, J. Piątkowski, A. Kajetanowicz*, K. Grela*
Synlett, 2019, 30(17): 1981-1987, DOI: 10.1055/s-0037-1611834