Overview
Subprogram I: Molecular machines and light-responsive materials
Molecular motors:
- Design and synthesis of novel molecular photoswitches and light-powered molecular machines;
- Development of new scaffolds of light-driven molecular motors;
- Optimization of operational efficiency of light-driven molecular machines;
Photo-responsive materials:
- Design and synthesis of novel photo-responsive porous materials based on MOF, COF and HOF;
- Novel synthetic methodologies for construction of porous materials with tailored morphologies;
- Design and synthesis of novel light-orthogonal systems based on block copolymers;
- Construction of isoporous membranes based on amphiphilic stimuli-responsive polymers.
Researchers: dr inż. W. Danowski, mgr P. Cieciórski
Subprogram II: Polymer chemistry
- Synthesis of photocatalysts excited by visible or NIR light and study of the influence of their structure on the kinetics of photo-RDRP polymerization;
- Searching for new monomers enabling depolymerization of corresponding polymers in mild conditions;
- Development of new, biocompatible photo-RDRP methods in aqueous solutions and air atmosphere.
Researchers: dr G. Szczepaniak, dr M. Cybularczyk-Cecotka
Subprogram III: Catalysis and nanotechnology
- Development of new, environmentally friendly methods of obtaining chemical compounds important in the industry;
- Design and synthesis of new catalysts for selected organic processes;
- Synthesis and characterization of metal nanoparticles;
- Activation of small molecules (CO, CO2, O2);
- Organic processes carried out under increased pressure in the presence of nanocatalysts;
- Functionalization of C60/C70 fullerenes, Sc3N@C80, Lu3N@C80, Gd@C82 metal fullerenes and graphene for applications in photovoltaics, catalysis and medicine;
- New materials for applications in optoelectronics – structural research and electronic properties using DFT computational methods.
Researchers: dr hab. A. Kaim, dr P. Piotrowski, dr A. Krogul-Sobczak, mgr S. Lukato
Subprogram IV: Interfacial processes in biomimetic systems
- Studies of the kinetics of lipid oxidation;
- Investigation of phenomena occurring at the liquid-liquid interface, in particular the interfacial transport of biologically active molecules;
- Studies of qualitative and quantitative description of small molecules between coexisting solvent phases and micellar phases;
- Study of encapsulation of biologically active molecules in micellar structures;
- Study of interactions of substances with potential antioxidant properties with model lipid membranes;
- Influence of solvent effects on the inhibition of the autooxidation process.
Researchers: dr H. Wilczura-Wachnik, dr inż. K. Jodko-Piórecka, dr A. Krogul-Sobczak, dr A. Konopko, dr inż. J. Cędrowski, mgr J. Kusio, mgr P. Przybylski
Subprogram V: Antioxidants
Chemistry of antioxidants:
- Physicochemical basis of antioxidant activity: from solvent effects and mechanistic studies to interfacial phenomena in biomimetic systems;
- New hybrid antioxidants containing nitroxide and phenolic functional groups – research in chemical and biological systems;
- New nanoparticle antioxidants: design, synthesis and study of the mechanism of action for potential applications;
- Study of the fluorescent properties of the peroxyl radical sensor as a marker of oxidative stress in lipid membranes;
- A senolytic nanoplatform based on electrospun nanofibers delivering nutraceutical derivatives to remove breast cancer cells with chemotherapeutic-induced aging;
- Searching for mechanisms of antioxidant activity of selected organic nitrogen and sulphur compounds.
Researchers: dr inż. K. Jodko-Piórecka, dr M. Cybularczyk-Cecotka, dr A. Konopko, mgr J. Kusio, mgr P. Przybylski
Synthesis of novel antioxidants:
- Design and synthesis of peroxyl radical sensors based on BODIPY;
- Construction of new hybrid antioxidants containing nitroxide and phenolic functional groups;
- Modification of well-known natural antioxidants (based on flavonoids, isothiocyanates).
Researchers: dr M. Cybularczyk-Cecotka, dr inż. J. Cędrowski, mgr J. Kusio, mgr W. Witkowski