Wdowik’s Group
| Wdowik Research Group
Group members
Group Leader:
Postdoctoral Researchers:
Students:
Zofia Porębska
Maria Świątkowska
Research
- Investigation of selective transition-metal-catalyzed C–H activation strategies for modified N-heterocycles.
- Design and optimization of novel methodologies for single-atom editing in complex organic molecules.
- Development of catalytic methods for the synthesis of heterocycles.
- Application of developed methodologies in the late-stage functionalization of bioactive and pharmaceutical compounds.
Selected publications
- Copper-Catalyzed Enantioselective Aerobic Alkene Aminooxygenation and Dioxygenation: Access to 2-Formyl Saturated Heterocycles and Unnatural Proline Derivatives,
Journal of the American Chemical Society, 2023 - Enantioselective palladaelectro-catalyzed C–H olefinations and allylations for N–C axial chirality,
Chemical Science, 2021 - Enantioselective, Aerobic Copper-Catalyzed Intramolecular Carboamination and Carboetherification of Unactivated Alkenes,
ACS Catalysis, 2020 - Enantioselective Pallada‐Electrocatalyzed C− H Activation by Transient Directing Groups: Expedient Access to Helicenes,
Angewandte Chemie International Edition, 2020 - Direct Synthesis of 2-Formylpyrrolidines, 2-Pyrrolidinones and 2-Dihydrofuranones via Aerobic Copper-Catalyzed Aminooxygenation and Dioxygenation of 4-Pentenylsulfonamides and 4-Pentenylalcohols,
Journal of the American Chemical Society, 2017
Funding
Late-stage C–H functionalization of complex molecules aided by single-atom editing
PI: T. Wdowik
2024-2027, 1.753.140 PLN
Sonata 19, (2023/51/D/ST5/02947), National Science Centre
