Litwinienko’s Group

• Development of new, environmentally friendly methods of obtaining chemical compounds important in the industry;
• Design and synthesis of new catalysts for selected organic processes;
• Synthesis and characterization of metal nanoparticles;
• Activation of small molecules (CO, CO2, O2);
• Organic processes carried out under increased pressure in the presence of nanocatalysts;
• Functionalization of C60/C70 fullerenes, Sc3N@C80, Lu3N@C80, Gd@C82 metal fullerenes and graphene for applications in photovoltaics, catalysis and medicine;
• New materials for applications in optoelectronics – structural research and electronic properties using DFT computational methods.

Selected publications:

• Silver Nanoparticles Densely Grafted with Nitroxides as a Recyclable Green Catalyst in the Selective Oxidation of Alcohols, Nanomaterials, 2022
• Crystal structure, electronic properties and cytotoxic activity of palladium chloride complexes with monosubstituted pyridines, Dalton Transactions, 2012
• Impact of the aliphatic side chain length on photovoltaic properties of fullerenes functionalized with 3-(1-indenyl)propionic acid esters, New Journal of Chemistry, 2024
• Fullerene modification of gold electrodes and gold nanoparticles based on application of aromatic thioacetate-functionalized C60, RSC Advances, 2014

All publications

• Studies of the kinetics of lipid oxidation;
• Investigation of phenomena occurring at the liquid-liquid interface, in particular the interfacial transport of biologically active molecules;
• Studies of qualitative and quantitative description of small molecules between coexisting solvent phases and micellar phases;
• Study of encapsulation of biologically active molecules in micellar structures;
• Study of interactions of substances with potential antioxidant properties with model lipid membranes;
• Influence of solvent effects on the inhibition of the autooxidation process.

Selected publications:

All publications

Chemistry of antioxidants:

• Physicochemical basis of antioxidant activity: from solvent effects and mechanistic studies to interfacial phenomena in biomimetic systems;
• New hybrid antioxidants containing nitroxide and phenolic functional groups – research in chemical and biological systems;
• New nanoparticle antioxidants: design, synthesis and study of the mechanism of action for potential applications;
• Study of the fluorescent properties of the peroxyl radical sensor as a marker of oxidative stress in lipid membranes;
• A senolytic nanoplatform based on electrospun nanofibers delivering nutraceutical derivatives to remove breast cancer cells with chemotherapeutic-induced aging;
• Searching for mechanisms of antioxidant activity of selected organic nitrogen and sulphur compounds.

Synthesis of novel antioxidants:

• Design and synthesis of peroxyl radical sensors based on BODIPY;
• Construction of new hybrid antioxidants containing nitroxide and phenolic functional groups;
• Modification of well-known natural antioxidants (based on flavonoids, isothiocyanates).

Selected publications:

All publications