New paper in Free Radical Biology and Medicine
27 01 2025
Category: Publications
Check out recent study co-authored by Dr. Piotr Piotrowski and Prof. Grzegorz Litwinienko, in collaboration with the University of Łódź, the University of Silesia, and the University of Messina, explores the biomedical potential of metallofullerenols and fullerenols. Focusing on the fullerene derivatives Gd@C82(OH)22 and C70(OH)12, the research highlights their protective effects on erythrocyte membranes under oxidative stress. The study reveals that Gd@C82(OH)22, with its enhanced antioxidant properties due to gadolinium encapsulation, offers superior preservation of membrane integrity, lipid bilayer stability, and protein function. These findings underline the therapeutic promise of Gd@C82(OH)22 in combating oxidative damage, paving the way for biomedical innovations.
Read more about this research:
Metallofullerenol Gd@C82(OH)22 preserves human erythrocyte plasma membrane integrity from AAPH-induced oxidative stress: molecular mechanisms and antioxidant activity
A. Remigante, M. Studzian, S. Spinelli, P. Piotrowski, G. Litwinienko, K. Gorny, P. Raczynski, A. Marino, R. Morabito, J. Grebowski*